A Cell-Based Screen Identifies HDAC Inhibitors as Activators of RIG-I Signaling

Enhancing the immune microenvironment in cancer by targeting the nucleic acid sensors is becoming a potent therapeutic strategy. Among the nucleic acid sensors, activation of the RNA sensor Retinoic Acid-inducible Gene (RIG-I) using small hairpin RNAs has been shown to elicit powerful innate and ada...

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Detalles Bibliográficos
Autores principales: Fraile-Bethencourt, Eugenia, Foss, Marie H., Nelson, Dylan, Malhotra, Sanjay V., Anand, Sudarshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882870/
https://www.ncbi.nlm.nih.gov/pubmed/35237663
http://dx.doi.org/10.3389/fmolb.2022.837610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882870/
https://www.ncbi.nlm.nih.gov/pubmed/35237663
http://dx.doi.org/10.3389/fmolb.2022.837610

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