Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase

Reverse transcriptase (RT) from the human immunodeficiency virus continues to be an attractive drug target for antiretroviral therapy. June 2022 will commemorate the 30th anniversary of the first Human Immunodeficiency Virus (HIV) RT crystal structure complex that was solved with non-nucleoside reve...

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Detalles Bibliográficos
Autores principales: Frey, Kathleen M., Bertoletti, Nicole, Chan, Albert H., Ippolito, Joseph A., Bollini, Mariela, Spasov, Krasimir A., Jorgensen, William L., Anderson, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882919/
https://www.ncbi.nlm.nih.gov/pubmed/35237658
http://dx.doi.org/10.3389/fmolb.2022.805187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882919/
https://www.ncbi.nlm.nih.gov/pubmed/35237658
http://dx.doi.org/10.3389/fmolb.2022.805187

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