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Noncanonical Wnt5a Signaling Suppresses Hippo/TAZ-Mediated Osteogenesis Partly Through the Canonical Wnt Pathway in SCAPs

PURPOSE: Stem cells from the apical papilla (SCAPs) are promising seed cells for tissue regeneration medicine and possess the osteogenic differentiation potential. Wnt5a, a typical ligand of the noncanonical Wnt pathway, exhibits diverse roles in the regulation of osteogenesis. The transcriptional c...

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Detalles Bibliográficos
Autores principales: Fu, Yajing, Ma, Dan, Fan, Fengyan, Sun, Tongke, Han, Ruiqi, Yang, Yanran, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882979/
https://www.ncbi.nlm.nih.gov/pubmed/35237028
http://dx.doi.org/10.2147/DDDT.S350698