Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque

Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in 2019 has rapidly expanded into a serious global pandemic. Due to the high morbidity and mortality of COVID-19, there is an urgent need to develop safe and effective vaccines. AdC68-1...

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Detalles Bibliográficos
Autores principales: Dai, Xuedong, Zhao, Weijun, Tong, Xin, Liu, Wei, Zeng, Xianhuan, Duan, Xiaohui, Wu, Hua, Wang, Lili, Huang, Zhen, Tang, Xinying, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Immunotoxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883008/
https://www.ncbi.nlm.nih.gov/pubmed/35226134
http://dx.doi.org/10.1007/s00204-021-03221-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883008/
https://www.ncbi.nlm.nih.gov/pubmed/35226134
http://dx.doi.org/10.1007/s00204-021-03221-x

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