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Nivolumab-DTPA-Based PD-1 Imaging Reveals Structural and Pathological Changes in Colorectal Carcinoma

Programmed cell death protein 1 (PD-1) expression is considered a prognostic marker of tumor response to the immuno-blocking therapy. In this study, nivolumab was conjugated with diethylenetriamine pentaacetate (DTPA) via condensation reaction between amidogen and p-SCN-Bn-DTPA, which provided label...

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Detalles Bibliográficos
Autores principales: Li, Danni, Li, Xiao, Yang, Jian, Shi, Zhang, Zhang, Lu, Li, Rou, Peng, Ye, Liu, Jiajun, Zuo, Changjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883027/
https://www.ncbi.nlm.nih.gov/pubmed/35237584
http://dx.doi.org/10.3389/fbioe.2022.839756