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Baicalein Induces Mitochondrial Autophagy to Prevent Parkinson's Disease in Rats via miR-30b and the SIRT1/AMPK/mTOR Pathway

Parkinson's disease (PD) is a prevailing neurodegenerative disorder. Baicalein has neuroprotective effects on PD animals, but its mechanism is not clarified. We explored baicalein effects on PD rats. PD rat models were established by injecting 6-hydroxydopamine into the striatum of substantia n...

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Detalles Bibliográficos
Autores principales: Chen, Min, Peng, Li, Gong, Ping, Zheng, Xiaoli, Sun, Tao, Zhang, Xiaoqiao, Huo, Jiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883053/
https://www.ncbi.nlm.nih.gov/pubmed/35237220
http://dx.doi.org/10.3389/fneur.2021.646817