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PNP Hydrogel Prevents Formation of Symblephara in Mice After Ocular Alkali Injury

PURPOSE: To create an alkali injury symblephara mouse model to study conjunctival fibrosis pathophysiology and test polymer nanoparticle (PNP) hydrogel as a preventative therapeutic. METHODS: Mice were injured using NaOH-soaked filter paper to determine the optimal NaOH concentration to induce the f...

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Detalles Bibliográficos
Autores principales: Swarup, Aditi, Grosskopf, Abigail K., Stapleton, Lindsay M., Subramaniam, Varun R., Li, BaoXiang, Weissman, Irving L., Appel, Eric A., Wu, Albert Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883170/
https://www.ncbi.nlm.nih.gov/pubmed/35191963
http://dx.doi.org/10.1167/tvst.11.2.31