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Does DNA methylation mediate the association of age at puberty with forced vital capacity or forced expiratory volume in 1 s?

BACKGROUND: Age of pubertal onset is associated with lung function in adulthood. However, the underlying role of epigenetics as a mediator of this association remains unknown. METHODS: DNA methylation (DNAm) in peripheral blood was measured at age 18 years in the Isle of Wight birth cohort (IOWBC) a...

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Detalles Bibliográficos
Autores principales: Li, Liang, Zhang, Hongmei, Holloway, John W., Ewart, Susan, Relton, Caroline L., Arshad, S. Hasan, Karmaus, Wilfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883177/
https://www.ncbi.nlm.nih.gov/pubmed/35237685
http://dx.doi.org/10.1183/23120541.00476-2021