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Single-stranded RNA viruses activate and hijack host apical DNA damage response kinases for efficient viral replication
The ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) are apical kinases that orchestrate the multifaceted DNA damage response (DDR) to a variety of genotoxic insults and regulate genomic stability. Whether RNA virus also manipulates the host’s DDR machine to facilitate replication is l...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883245/ https://www.ncbi.nlm.nih.gov/pubmed/35252763 http://dx.doi.org/10.1007/s42764-022-00064-3 |