Single-stranded RNA viruses activate and hijack host apical DNA damage response kinases for efficient viral replication

The ataxia-telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) are apical kinases that orchestrate the multifaceted DNA damage response (DDR) to a variety of genotoxic insults and regulate genomic stability. Whether RNA virus also manipulates the host’s DDR machine to facilitate replication is l...

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Detalles Bibliográficos
Autores principales: Li, Pengcheng, Xu, Chenchen, Zhang, Xiaoyan, Cao, Cheng, Wang, Xuejuan, Cai, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883245/
https://www.ncbi.nlm.nih.gov/pubmed/35252763
http://dx.doi.org/10.1007/s42764-022-00064-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883245/
https://www.ncbi.nlm.nih.gov/pubmed/35252763
http://dx.doi.org/10.1007/s42764-022-00064-3

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