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Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3Kγ inhibitor can enhance immunogenicity and eradicate tumors

BACKGROUND: With the rapid development of immune checkpoint inhibitors and neoantigen (NeoV)-based personalized tumor vaccines, tumor immunotherapy has shown promising therapeutic results. However, the limited efficacy of available tumor vaccines impedes the development of personalized tumor immunot...

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Detalles Bibliográficos
Autores principales: Du, Yang, Liu, Ye, Wang, Di, Bai, Hua, Wang, Zhijie, He, Xiran, Zhang, Pei, Tian, Jie, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883272/
https://www.ncbi.nlm.nih.gov/pubmed/35217574
http://dx.doi.org/10.1136/jitc-2021-003564