Neurofilament Light Regulates Axon Caliber, Synaptic Activity, and Organelle Trafficking in Cultured Human Motor Neurons

Neurofilament light (NFL) is one of the proteins forming multimeric neuron-specific intermediate filaments, neurofilaments, which fill the axonal cytoplasm, establish caliber growth, and provide structural support. Dominant missense mutations and recessive nonsense mutations in the neurofilament lig...

Descripción completa

Detalles Bibliográficos
Autores principales: Sainio, Markus T., Rasila, Tiina, Molchanova, Svetlana M., Järvilehto, Julius, Torregrosa-Muñumer, Rubén, Harjuhaahto, Sandra, Pennonen, Jana, Huber, Nadine, Herukka, Sanna-Kaisa, Haapasalo, Annakaisa, Zetterberg, Henrik, Taira, Tomi, Palmio, Johanna, Ylikallio, Emil, Tyynismaa, Henna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883324/
https://www.ncbi.nlm.nih.gov/pubmed/35237613
http://dx.doi.org/10.3389/fcell.2021.820105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883324/
https://www.ncbi.nlm.nih.gov/pubmed/35237613
http://dx.doi.org/10.3389/fcell.2021.820105

Ejemplares similares