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Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium

Oral exposure to hexavalent chromium (Cr(VI)) induces tumors in the mouse duodenum. Previous microarray-based transcriptomic analyses of homogenized mouse duodenal tissue have demonstrated Cr(VI)-induced alterations in various cellular pathways and processes. However, X-ray fluorescence microscopy i...

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Detalles Bibliográficos
Autores principales: Chappell, Grace A, Wolf, Jeffrey C, Thompson, Chad M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883354/
https://www.ncbi.nlm.nih.gov/pubmed/34935971
http://dx.doi.org/10.1093/toxsci/kfab152