Cargando…

Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium

Oral exposure to hexavalent chromium (Cr(VI)) induces tumors in the mouse duodenum. Previous microarray-based transcriptomic analyses of homogenized mouse duodenal tissue have demonstrated Cr(VI)-induced alterations in various cellular pathways and processes. However, X-ray fluorescence microscopy i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chappell, Grace A, Wolf, Jeffrey C, Thompson, Chad M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Genetic and Epigenetic Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883354/ https://www.ncbi.nlm.nih.gov/pubmed/34935971 http://dx.doi.org/10.1093/toxsci/kfab152

Ejemplares similares

Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens
por: Chappell, Grace A, et al.
Publicado: (2021)

Comparison of the Effects of Hexavalent Chromium in the Alimentary Canal of F344 Rats and B6C3F1 Mice Following Exposure in Drinking Water: Implications for Carcinogenic Modes of Action
por: Thompson, Chad M., et al.
Publicado: (2012)

Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA
por: Heintz, Melissa M., et al.
Publicado: (2022)

Mapping the Duodenal Crypt-Villus Transport Axis
por: Barrett, Kim E.
Publicado: (2018)

Transcriptome Profile Analysis of Intestinal Upper Villus Epithelial Cells and Crypt Epithelial Cells of Suckling Piglets
por: Zou, Lijun, et al.
Publicado: (2022)

Immune niches orchestrated by intestinal mesenchymal stromal cells lining the crypt-villus
por: Sun, Hongxiang, et al.
Publicado: (2022)

Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes
por: Anderle, Pascale, et al.
Publicado: (2005)

Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis
por: Yang, Huansheng, et al.
Publicado: (2016)

The Intestinal Epithelium – Fluid Fate and Rigid Structure From Crypt Bottom to Villus Tip
por: Bonis, Vangelis, et al.
Publicado: (2021)

Production and characterization of avian crypt-villus enteroids and the effect of chemicals
por: Acharya, Mohan, et al.
Publicado: (2020)

A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration
por: Totonelli, Giorgia, et al.
Publicado: (2012)

Pattern recognition receptors in the gut: analysis of their expression along the intestinal tract and the crypt/villus axis
por: Gourbeyre, Pascal, et al.
Publicado: (2015)

A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche
por: Xiang, Jinnan, et al.
Publicado: (2023)

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer†
por: Thompson, Chad M, et al.
Publicado: (2014)

Intestinal Morphogenesis in Development, Regeneration, and Disease: The Potential Utility of Intestinal Organoids for Studying Compartmentalization of the Crypt-Villus Structure
por: Kwon, Ohman, et al.
Publicado: (2020)

Hexavalent chromium (Contaminants)
Publicado: (2019)

The role of perfluorooctane sulfonic acid (PFOS) exposure in inflammation of intestinal tissues and intestinal carcinogenesis
por: Durham, Jerika, et al.
Publicado: (2023)

Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function
por: Altay, Gizem, et al.
Publicado: (2019)

HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium
por: Murray, Elisa, et al.
Publicado: (2021)

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans
por: Thompson, Chad M., et al.
Publicado: (2013)

The link between deacetylation and hepatotoxicity induced by exposure to hexavalent chromium
por: Yang, Qingyue, et al.
Publicado: (2021)

The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine
por: Muglia, C, et al.
Publicado: (2011)

Overexpression of CD98 in intestinal epithelium dysregulates miRNAs and their targeted proteins along the ileal villus-crypt axis
por: Han, Moon K., et al.
Publicado: (2018)

Author Correction: Self-organized intestinal epithelial monolayers in crypt and villus-like domains show effective barrier function
por: Altay, Gizem, et al.
Publicado: (2019)

Biomarkers of Human Exposure to Acrylamide and Relation to Polymorphisms in Metabolizing Genes
por: Duale, Nur, et al.
Publicado: (2009)

Effect of prenatal exposure to combined immunosuppressive agrochemicals in a mouse model of allergic airway inflammation
por: TAJIKI-NISHINO, Risako, et al.
Publicado: (2019)

Selenium regulates Nrf2 signaling to prevent hepatotoxicity induced by hexavalent chromium in broilers
por: Wang, Jingqiu, et al.
Publicado: (2022)

Biosorption of hexavalent chromium by Pleurotus ostreatus
por: da Rocha Ferreira, Glalber Luiz, et al.
Publicado: (2019)

Effects of Prenatal Exposure to Titanium Dioxide Nanoparticles on DNA Methylation and Gene Expression Profile in the Mouse Brain
por: Tachibana, Ken, et al.
Publicado: (2021)

Bioremediation of Hexavalent Chromium by Chromium Resistant Bacteria Reduces Phytotoxicity
por: Hossan, Shanewaz, et al.
Publicado: (2020)

Derivation of New Threshold of Toxicological Concern Values for Exposure via Inhalation for Environmentally-Relevant Chemicals
por: Nelms, Mark D., et al.
Publicado: (2020)

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin‐of‐exposure values for hexavalent chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium
por: Thompson, Chad M., et al.
Publicado: (2017)

PepT1 Expression Helps Maintain Intestinal Homeostasis by Mediating the Differential Expression of miRNAs along the Crypt-Villus Axis
por: Zhang, Yuchen, et al.
Publicado: (2016)

Apolipoprotein A4 Defines the Villus-Crypt Border in Duodenal Specimens for Celiac Disease Morphometry
por: Taavela, Juha, et al.
Publicado: (2021)

Phytofabrication of Iron Nanoparticles for Hexavalent Chromium Remediation
por: Truskewycz, Adam, et al.
Publicado: (2018)

Adverse hematological effects of hexavalent chromium: an overview
por: Ray, Rina Rani
Publicado: (2016)

Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers
por: Zhang, Xu-Hui, et al.
Publicado: (2011)

Congeners-Specific Intestinal Absorption Of Microcystins In An In Vitro 3D Human Intestinal Epithelium: The Role Of Influx/Efflux Transporters
por: Turco, Laura, et al.
Publicado: (2022)

Editorial: Occupational exposure to nanomaterials
por: Andraos, Charlene, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tsotkmeojfvd6jnn7fvig9uehb