SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis

Background: Inflammatory osteolysis induced by wear particles is the major cause of prosthetic loosening after artificial joint replacement, and its prevention and treatment are difficult worldwide. Our previous study confirmed that sphingosine kinases (SPHKs) are important mediators regulating the...

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Detalles Bibliográficos
Autores principales: Gu, Minghui, Pan, Baiqi, Chen, Weishen, Xu, Hai, Wu, Xiaoyu, Hu, Xuantao, Zheng, Linli, Ye, Yongyu, Meng, Qing, Xian, Guoyan, Zhang, Ziji, Sheng, Puyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883393/
https://www.ncbi.nlm.nih.gov/pubmed/35237148
http://dx.doi.org/10.3389/fphar.2021.794429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883393/
https://www.ncbi.nlm.nih.gov/pubmed/35237148
http://dx.doi.org/10.3389/fphar.2021.794429

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