Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology

[Image: see text] Compelling new support has been provided for histone deacetylase isoform 6 (HDAC6) as a common thread in the generation of the dysregulated proinflammatory and fibrotic phenotype in cystic fibrosis (CF). HDAC6 also plays a crucial role in bacterial clearance or killing as a direct...

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Detalles Bibliográficos
Autores principales: Barone, Simona, Cassese, Emilia, Alfano, Antonella Ilenia, Brindisi, Margherita, Summa, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883472/
https://www.ncbi.nlm.nih.gov/pubmed/35148101
http://dx.doi.org/10.1021/acs.jmedchem.1c02067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883472/
https://www.ncbi.nlm.nih.gov/pubmed/35148101
http://dx.doi.org/10.1021/acs.jmedchem.1c02067

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