Site-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9

[Image: see text] Ubiquitylation—the attachment of ubiquitin (Ub) to proteins in eukaryotic cells—involves a vast number of enzymes from three different classes, resulting in heterogeneous attachment sites and ubiquitin chains. Recently, we introduced lysine acylation using conjugating enzymes (LACE...

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Detalles Bibliográficos
Autores principales: Akimoto, Gaku, Fernandes, Arianna P., Bode, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883482/
https://www.ncbi.nlm.nih.gov/pubmed/35237717
http://dx.doi.org/10.1021/acscentsci.1c01490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883482/
https://www.ncbi.nlm.nih.gov/pubmed/35237717
http://dx.doi.org/10.1021/acscentsci.1c01490

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