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Site-Specific Protein Ubiquitylation Using an Engineered, Chimeric E1 Activating Enzyme and E2 SUMO Conjugating Enzyme Ubc9
[Image: see text] Ubiquitylation—the attachment of ubiquitin (Ub) to proteins in eukaryotic cells—involves a vast number of enzymes from three different classes, resulting in heterogeneous attachment sites and ubiquitin chains. Recently, we introduced lysine acylation using conjugating enzymes (LACE...
Autores principales: | Akimoto, Gaku, Fernandes, Arianna P., Bode, Jeffrey W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883482/ https://www.ncbi.nlm.nih.gov/pubmed/35237717 http://dx.doi.org/10.1021/acscentsci.1c01490 |
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