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N-terminal phosphorylation regulates the activity of glycogen synthase kinase 3 from Plasmodium falciparum

As the decline of malaria cases stalled over the last five years, novel targets in Plasmodium falciparum are necessary for the development of new drugs. Glycogen Synthase Kinase (PfGSK3) has been identified as a potential target, since its selective inhibitors were shown to disrupt the parasitès lif...

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Detalles Bibliográficos
Autores principales: Pazicky, Samuel, Alder, Arne, Mertens, Haydyn, Svergun, Dmitri, Gilberger, Tim, Löw, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883495/
https://www.ncbi.nlm.nih.gov/pubmed/35023554
http://dx.doi.org/10.1042/BCJ20210829