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TAT–RHIM: a more complex issue than expected

Murine cytomegalovirus protein M45 contains a RIP homotypic interaction motif (RHIM) that is sufficient to confer protection of infected cells against necroptotic cell death. Mechanistically, the N-terminal region of M45 drives rapid self-assembly into homo-oligomeric amyloid fibrils, and interacts...

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Detalles Bibliográficos
Autores principales: Kolbrink, Benedikt, Riebeling, Theresa, Teiwes, Nikolas K., Steinem, Claudia, Kalbacher, Hubert, Kunzendorf, Ulrich, Krautwald, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883498/
https://www.ncbi.nlm.nih.gov/pubmed/35015082
http://dx.doi.org/10.1042/BCJ20210677