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TAT–RHIM: a more complex issue than expected
Murine cytomegalovirus protein M45 contains a RIP homotypic interaction motif (RHIM) that is sufficient to confer protection of infected cells against necroptotic cell death. Mechanistically, the N-terminal region of M45 drives rapid self-assembly into homo-oligomeric amyloid fibrils, and interacts...
Autores principales: | Kolbrink, Benedikt, Riebeling, Theresa, Teiwes, Nikolas K., Steinem, Claudia, Kalbacher, Hubert, Kunzendorf, Ulrich, Krautwald, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883498/ https://www.ncbi.nlm.nih.gov/pubmed/35015082 http://dx.doi.org/10.1042/BCJ20210677 |
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