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Sox2 overexpression alleviates noise-induced hearing loss by inhibiting inflammation-related hair cell apoptosis

BACKGROUND: The transcription factor Sox2 plays important roles in the developmental processes of multiple organs and tissues. However, whether Sox2 can protect mature or terminally differentiated cells against injury is still unknown. METHODS: We investigated the roles of Sox2 in cochlear hair cell...

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Detalles Bibliográficos
Autores principales: Chen, Diyan, Jia, Gaogan, Zhang, Yanping, Mao, Huanyu, Zhao, Liping, Li, Wenyan, Chen, Yan, Ni, Yusu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883703/
https://www.ncbi.nlm.nih.gov/pubmed/35227273
http://dx.doi.org/10.1186/s12974-022-02414-0