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Distributional regression in clinical trials: treatment effects on parameters other than the mean

BACKGROUND: The classical linear model is widely used in the analysis of clinical trials with continuous outcomes. However, required model assumptions are frequently not met, resulting in estimates of treatment effect that can be inefficient and biased. In addition, traditional models assess treatme...

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Detalles Bibliográficos
Autores principales: Heller, Gillian Z., Robledo, Kristy P., Marschner, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883706/
https://www.ncbi.nlm.nih.gov/pubmed/35220944
http://dx.doi.org/10.1186/s12874-022-01534-8