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Functional Changes of Therapeutic Antibodies upon Exposure to Pro-Oxidative Agents

Therapeutic monoclonal antibodies have exerted a transformative impact on clinical practice in last two decades. However, development of a therapeutic antibody remains a complex process. Various physiochemical and functional liabilities can compromise the production or the therapeutic efficacy of an...

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Detalles Bibliográficos
Autores principales: Lecerf, Maxime, Lacombe, Robin, Kanyavuz, Alexia, Dimitrov, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8883895/
https://www.ncbi.nlm.nih.gov/pubmed/35225869
http://dx.doi.org/10.3390/antib11010011