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Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation

Single‐cell technologies are revolutionizing biology but are today mainly limited to imaging and deep sequencing. However, proteins are the main drivers of cellular function and in‐depth characterization of individual cells by mass spectrometry (MS)‐based proteomics would thus be highly valuable and...

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Detalles Bibliográficos
Autores principales: Brunner, Andreas‐David, Thielert, Marvin, Vasilopoulou, Catherine, Ammar, Constantin, Coscia, Fabian, Mund, Andreas, Hoerning, Ole B, Bache, Nicolai, Apalategui, Amalia, Lubeck, Markus, Richter, Sabrina, Fischer, David S, Raether, Oliver, Park, Melvin A, Meier, Florian, Theis, Fabian J, Mann, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884154/
https://www.ncbi.nlm.nih.gov/pubmed/35226415
http://dx.doi.org/10.15252/msb.202110798