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Downregulation of Three Immune-Specific Core Genes and the Regulatory Pathways in Children and Adult Friedreich's Ataxia: A Comprehensive Analysis Based on Microarray

BACKGROUND: Friedreich's ataxia (FRDA) is a familial hereditary disorder that lacks available therapy. Therefore, the identification of novel biomarkers and key mechanisms related to FRDA progression is urgently required. METHODS: We identified the up-regulated and down-regulated differentially...

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Detalles Bibliográficos
Autores principales: Liu, Lichun, Lai, Yongxing, Zhan, Zhidong, Fu, Qingxian, Jiang, Yuelian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884172/
https://www.ncbi.nlm.nih.gov/pubmed/35237223
http://dx.doi.org/10.3389/fneur.2021.816393