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Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks
Repair of DNA Double-Strand Breaks (DSBs) can be error-free or highly mutagenic, depending on which of multiple mechanistically distinct pathways repairs the break. Hence, DSB-repair pathway choice directly affects genome integrity, and it is therefore of interest to understand the parameters that d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884240/ https://www.ncbi.nlm.nih.gov/pubmed/35237296 http://dx.doi.org/10.3389/fgene.2021.809832 |