p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons

p140Cap, encoded by the gene SRCIN1 (SRC kinase signaling inhibitor 1), is an adaptor/scaffold protein highly expressed in the mouse brain, participating in several pre- and post-synaptic mechanisms. p140Cap knock-out (KO) female mice show severe hypofertility, delayed puberty onset, altered estrus...

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Detalles Bibliográficos
Autores principales: Camera, Mattia, Russo, Isabella, Zamboni, Valentina, Ammoni, Alessandra, Rando, Simona, Morellato, Alessandro, Cimino, Irene, Angelini, Costanza, Giacobini, Paolo, Oleari, Roberto, Amoruso, Federica, Cariboni, Anna, Franceschini, Isabelle, Turco, Emilia, Defilippi, Paola, Merlo, Giorgio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884249/
https://www.ncbi.nlm.nih.gov/pubmed/35237119
http://dx.doi.org/10.3389/fnins.2022.744693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884249/
https://www.ncbi.nlm.nih.gov/pubmed/35237119
http://dx.doi.org/10.3389/fnins.2022.744693

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