17R/S-Benzo-RvD1, a synthetic resolvin D1 analogue, attenuates neointimal hyperplasia in a rat model of acute vascular injury

BACKGROUND: Persistent inflammation following vascular injury drives neointimal hyperplasia (NIH). Specialized lipid mediators (SPM) mediate resolution which attenuates inflammation and downstream NIH. We investigated the effects of a synthetic analogue of resolvin D1 (RvD1) on vascular cells and in...

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Detalles Bibliográficos
Autores principales: Kim, Alexander S., Werlin, Evan C., Kagaya, Hideo, Chen, Mian, Wu, Bian, Mottola, Giorgio, Jan, Masood, Conte, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884511/
https://www.ncbi.nlm.nih.gov/pubmed/35226675
http://dx.doi.org/10.1371/journal.pone.0264217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884511/
https://www.ncbi.nlm.nih.gov/pubmed/35226675
http://dx.doi.org/10.1371/journal.pone.0264217

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