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Selection and Modelling of a New Single-Domain Intrabody Against TDP-43

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated to deteriorating motor and cognitive functions, and short survival. The disease is caused by neuronal death which results in progressive muscle wasting and weakness, ultimately leading to lethal respiratory failure. The m...

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Detalles Bibliográficos
Autores principales: Gilodi, Martina, Lisi, Simonetta, F. Dudás, Erika, Fantini, Marco, Puglisi, Rita, Louka, Alexandra, Marcatili, Paolo, Cattaneo, Antonino, Pastore, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884700/
https://www.ncbi.nlm.nih.gov/pubmed/35237655
http://dx.doi.org/10.3389/fmolb.2021.773234