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Serum Levels of IL-1 RA Increase with Obesity and Type 2 Diabetes in Relation to Adipose Tissue Dysfunction and are Reduced After Bariatric Surgery in Parallel to Adiposity

BACKGROUND: Excess adiposity leads to a dysfunctional adipose tissue that contributes to the development of obesity-associated comorbidities such as type 2 diabetes (T2D). Interleukin-1 receptor antagonist (IL-1RA) is a naturally occurring antagonist of the IL-1 receptor with anti-inflammatory prope...

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Detalles Bibliográficos
Autores principales: Frühbeck, Gema, Catalán, Victoria, Ramírez, Beatriz, Valentí, Víctor, Becerril, Sara, Rodríguez, Amaia, Moncada, Rafael, Baixauli, Jorge, Silva, Camilo, Escalada, Javier, Gómez-Ambrosi, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884708/
https://www.ncbi.nlm.nih.gov/pubmed/35237063
http://dx.doi.org/10.2147/JIR.S354095