Cargando…

Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants

In model organisms, RNA-sequencing (RNA-seq) is frequently used to assess the effect of genetic mutations on cellular and developmental processes. Typically, animals heterozygous for a mutation are crossed to produce offspring with different genotypes. Resultant embryos are grouped by genotype to co...

Descripción completa

Detalles Bibliográficos
Autores principales: White, Richard J, Mackay, Eirinn, Wilson, Stephen W, Busch-Nentwich, Elisabeth M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884726/
https://www.ncbi.nlm.nih.gov/pubmed/35175196
http://dx.doi.org/10.7554/eLife.72825