Clinical Impacts of Copy Number Variations in B-cell Differentiation and Cell Cycle Control Genes in Pediatric B-cell Acute Lymphoblastic Leukemia: a Single Centre Experience

BACKGROUND: IKZF1 gene deletions have been identified as a poor prognostic factor in pediatric B-cell acute lymphoblastic leukemia (B-ALL), especially in the presence of co-occurring deletions (IKZF1(plus) profile). This study aimed to determine the frequency of IKZF1 deletions and deletions in othe...

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Detalles Bibliográficos
Autores principales: Crepinsek, Klementina, Marinsek, Gasper, Kavcic, Marko, Prelog, Tomaž, Kitanovski, Lidija, Jazbec, Janez, Debeljak, Marusa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884847/
https://www.ncbi.nlm.nih.gov/pubmed/34957727
http://dx.doi.org/10.2478/raon-2021-0050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884847/
https://www.ncbi.nlm.nih.gov/pubmed/34957727
http://dx.doi.org/10.2478/raon-2021-0050

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