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Taking the STING out of acute myeloid leukemia through macrophage-mediated phagocytosis

Macrophages within the bone marrow (BM) microenvironment take on unexpected roles in acute myeloid leukemia (AML) as reported by Moore and colleagues in this issue of the JCI. In contrast to solid tumors, where tumor-associated macrophages frequently assume an immunosuppressive phenotype that promot...

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Detalles Bibliográficos
Autores principales: Dalton, William Brian, Ghiaur, Gabriel, Resar, Linda M.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884892/
https://www.ncbi.nlm.nih.gov/pubmed/35229728
http://dx.doi.org/10.1172/JCI157434