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NOTCH3 as a modulator of vascular disease: a target in elastin deficiency and arterial pathologies
During blood vessel disease, vascular smooth muscle cell (VSMC) expansion and interaction with the matrix trigger changes in gene expression and phenotype. In this issue of the JCI, Dave et al. discover a signaling network that drives VSMC expansion and vascular obstruction caused by elastin insuffi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884893/ https://www.ncbi.nlm.nih.gov/pubmed/35229725 http://dx.doi.org/10.1172/JCI157007 |