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NOTCH3 as a modulator of vascular disease: a target in elastin deficiency and arterial pathologies

During blood vessel disease, vascular smooth muscle cell (VSMC) expansion and interaction with the matrix trigger changes in gene expression and phenotype. In this issue of the JCI, Dave et al. discover a signaling network that drives VSMC expansion and vascular obstruction caused by elastin insuffi...

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Detalles Bibliográficos
Autores principales: Malka, Kimberly, Liaw, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884893/
https://www.ncbi.nlm.nih.gov/pubmed/35229725
http://dx.doi.org/10.1172/JCI157007