Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity

Piezo1 forms mechanically activated nonselective cation channels that contribute to endothelial response to fluid flow. Here we reveal an important role in the control of capillary density. Conditional endothelial cell–specific deletion of Piezo1 in adult mice depressed physical performance. Muscle...

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Detalles Bibliográficos
Autores principales: Bartoli, Fiona, Debant, Marjolaine, Chuntharpursat-Bon, Eulashini, Evans, Elizabeth L., Musialowski, Katie E., Parsonage, Gregory, Morley, Lara C., Futers, T. Simon, Sukumar, Piruthivi, Bowen, T. Scott, Kearney, Mark T., Lichtenstein, Laeticia, Roberts, Lee D., Beech, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884896/
https://www.ncbi.nlm.nih.gov/pubmed/35025768
http://dx.doi.org/10.1172/JCI141775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884896/
https://www.ncbi.nlm.nih.gov/pubmed/35025768
http://dx.doi.org/10.1172/JCI141775

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