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The hematopoietic saga of clonality in sickle cell disease

Sickle cell disease (SCD) is associated with an increased risk of vascular-occlusive events and of leukemia. Clonal hematopoiesis (CH) may increase both risks. In turn, physiologic abnormalities in SCD may modify the incidence and/or distribution of genetic alterations in CH. In a recent issue of th...

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Detalles Bibliográficos
Autores principales: Stonestrom, Aaron J., Levine, Ross L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884916/
https://www.ncbi.nlm.nih.gov/pubmed/35175224
http://dx.doi.org/10.1172/JCI158251