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The hematopoietic saga of clonality in sickle cell disease
Sickle cell disease (SCD) is associated with an increased risk of vascular-occlusive events and of leukemia. Clonal hematopoiesis (CH) may increase both risks. In turn, physiologic abnormalities in SCD may modify the incidence and/or distribution of genetic alterations in CH. In a recent issue of th...
Autores principales: | Stonestrom, Aaron J., Levine, Ross L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8884916/ https://www.ncbi.nlm.nih.gov/pubmed/35175224 http://dx.doi.org/10.1172/JCI158251 |
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