Cargando…

DNA folds threaten genetic stability and can be leveraged for chemotherapy

Damaging DNA is a current and efficient strategy to fight against cancer cell proliferation. Numerous mechanisms exist to counteract DNA damage, collectively referred to as the DNA damage response (DDR) and which are commonly dysregulated in cancer cells. Precise knowledge of these mechanisms is nec...

Descripción completa

Detalles Bibliográficos
Autores principales: Zell, Joanna, Rota Sperti, Francesco, Britton, Sébastien, Monchaud, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885165/
https://www.ncbi.nlm.nih.gov/pubmed/35340894
http://dx.doi.org/10.1039/d0cb00151a