Deferoxamine Inhibits Acute Lymphoblastic Leukemia Progression through Repression of ROS/HIF-1α, Wnt/β-Catenin, and p38MAPK/ERK Pathways

Acute lymphoblastic leukemia (ALL) is the most common type of childhood cancer, with a feature of easy to induce multidrug resistance and relapse. Abundant studies have proved that iron overload strengthens the growth and metastasis of tumor cells. Herein, we found that deferoxamine (DFO) effectivel...

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Detalles Bibliográficos
Autores principales: You, Hongliang, Wang, Dao, Wei, Linlin, Chen, Jiao, Li, Huanhuan, Liu, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885176/
https://www.ncbi.nlm.nih.gov/pubmed/35237325
http://dx.doi.org/10.1155/2022/8281267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885176/
https://www.ncbi.nlm.nih.gov/pubmed/35237325
http://dx.doi.org/10.1155/2022/8281267

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