A copper chaperone–mimetic polytherapy for SOD1-associated amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease in which motor neurons progressively and rapidly degenerate, eventually leading to death. The first protein found to contain ALS-associated mutations was copper/zinc superoxide dismutase 1 (SOD1), which is conformationally stable whe...

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Detalles Bibliográficos
Autores principales: McAlary, L., Shephard, V.K., Wright, G.S.A., Yerbury, J.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885447/
https://www.ncbi.nlm.nih.gov/pubmed/35065969
http://dx.doi.org/10.1016/j.jbc.2022.101612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885447/
https://www.ncbi.nlm.nih.gov/pubmed/35065969
http://dx.doi.org/10.1016/j.jbc.2022.101612

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