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In silico screening of neurokinin receptor antagonists as a therapeutic strategy for neuroinflammation in Alzheimer’s disease

Neuroinflammation is one of the detrimental factors leading to neurodegeneration in Alzheimer’s disease (AD) and other neurodegenerative disorders. The activation of microglial neurokinin 1 receptor (NK1R) by substance P (SP) enhances neuroinflammation which is mediated through pro-inflammatory path...

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Detalles Bibliográficos
Autores principales: Satarker, Sairaj, Maity, Swastika, Mudgal, Jayesh, Nampoothiri, Madhavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885547/
https://www.ncbi.nlm.nih.gov/pubmed/34331670
http://dx.doi.org/10.1007/s11030-021-10276-6