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The concurrent stimulation of Wnt and FGF8 signaling induce differentiation of dental mesenchymal cells into odontoblast-like cells

Fibroblast growth factor 8 (FGF8) is known to be a potent stimulator of canonical Wnt/β-catenin activity, an essential factor for tooth development. In this study, we analyzed the effects of co-administration of FGF8 and a CHIR99021 (GSK3β inhibitor) on differentiation of dental mesenchymal cells in...

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Detalles Bibliográficos
Autores principales: Kimura, Motoyoshi, Saito, Akiko, Onodera, Shoko, Nakamura, Takashi, Suematsu, Makoto, Shintani, Seikou, Azuma, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885561/
https://www.ncbi.nlm.nih.gov/pubmed/34739612
http://dx.doi.org/10.1007/s00795-021-00297-3