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The concurrent stimulation of Wnt and FGF8 signaling induce differentiation of dental mesenchymal cells into odontoblast-like cells
Fibroblast growth factor 8 (FGF8) is known to be a potent stimulator of canonical Wnt/β-catenin activity, an essential factor for tooth development. In this study, we analyzed the effects of co-administration of FGF8 and a CHIR99021 (GSK3β inhibitor) on differentiation of dental mesenchymal cells in...
Autores principales: | Kimura, Motoyoshi, Saito, Akiko, Onodera, Shoko, Nakamura, Takashi, Suematsu, Makoto, Shintani, Seikou, Azuma, Toshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885561/ https://www.ncbi.nlm.nih.gov/pubmed/34739612 http://dx.doi.org/10.1007/s00795-021-00297-3 |
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