PD-1 blockade enhances chemotherapy toxicity in oesophageal adenocarcinoma

Chemotherapy upregulates immune checkpoint (IC) expression on the surface of tumour cells and IC-intrinsic signalling confers a survival advantage against chemotherapy in several cancer-types including oesophageal adenocarcinoma (OAC). However, the signalling pathways mediating chemotherapy-induced...

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Detalles Bibliográficos
Autores principales: Davern, Maria, O’ Brien, Rebecca M., McGrath, Jason, Donlon, Noel E., Melo, Ashanty M., Buckley, Croí E., Sheppard, Andrew D., Reynolds, John V., Lynam-Lennon, Niamh, Maher, Stephen G., Lysaght, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885636/
https://www.ncbi.nlm.nih.gov/pubmed/35228614
http://dx.doi.org/10.1038/s41598-022-07228-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885636/
https://www.ncbi.nlm.nih.gov/pubmed/35228614
http://dx.doi.org/10.1038/s41598-022-07228-x

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