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An organ-derived extracellular matrix triggers in situ kidney regeneration in a preclinical model

It has not been considered that nephrons regenerate in adult mammals. We present that an organ-derived extracellular matrix in situ induces nephron regeneration in a preclinical model. A porcine kidney-derived extracellular matrix was sutured onto the surface of partial nephrectomy (PN)-treated kidn...

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Detalles Bibliográficos
Autores principales: Tajima, Kazuki, Yagi, Hiroshi, Morisaku, Toshinori, Nishi, Kotaro, Kushige, Hiroko, Kojima, Hideaki, Higashi, Hisanobu, Kuroda, Kohei, Kitago, Minoru, Adachi, Shungo, Natsume, Tohru, Nishimura, Kumiko, Oya, Mototsugu, Kitagawa, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885654/
https://www.ncbi.nlm.nih.gov/pubmed/35228532
http://dx.doi.org/10.1038/s41536-022-00213-y