High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers

Soluble HIV-1 envelope glycoprotein (Env) immunogens are a prime constituent of candidate vaccines designed to induce broadly neutralizing antibodies. Several lines of evidence suggest that enhancing Env immunogen thermostability can improve neutralizing antibody (NAb) responses. Here, we generated...

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Detalles Bibliográficos
Autores principales: del Moral-Sánchez, Iván, Russell, Rebecca A., Schermer, Edith E., Cottrell, Christopher A., Allen, Joel D., Torrents de la Peña, Alba, LaBranche, Celia C., Kumar, Sanjeev, Crispin, Max, Ward, Andrew B., Montefiori, David C., Sattentau, Quentin J., Sliepen, Kwinten, Sanders, Rogier W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885667/
https://www.ncbi.nlm.nih.gov/pubmed/35228534
http://dx.doi.org/10.1038/s41541-022-00446-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885667/
https://www.ncbi.nlm.nih.gov/pubmed/35228534
http://dx.doi.org/10.1038/s41541-022-00446-4

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