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Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs

Deep learning (DL) is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological data. However, progress in oligopeptide drug development has been limited, likely due to the lack of suitable datasets and difficul...

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Detalles Bibliográficos
Autores principales: Cai, Mingxiang, Xiao, Baichuan, Jin, Fujun, Xu, Xiaopeng, Hua, Yuwei, Li, Junhui, Niu, Pingping, Liu, Meijing, Wu, Jiaqi, Yue, Rui, Zhang, Yong, Wang, Zuolin, Zhang, Yongbiao, Wang, Xiaogang, Sun, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885677/
https://www.ncbi.nlm.nih.gov/pubmed/35228528
http://dx.doi.org/10.1038/s41413-022-00193-1