Cargando…
Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs
Deep learning (DL) is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of digitized biological data. However, progress in oligopeptide drug development has been limited, likely due to the lack of suitable datasets and difficul...
Autores principales: | Cai, Mingxiang, Xiao, Baichuan, Jin, Fujun, Xu, Xiaopeng, Hua, Yuwei, Li, Junhui, Niu, Pingping, Liu, Meijing, Wu, Jiaqi, Yue, Rui, Zhang, Yong, Wang, Zuolin, Zhang, Yongbiao, Wang, Xiaogang, Sun, Yao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885677/ https://www.ncbi.nlm.nih.gov/pubmed/35228528 http://dx.doi.org/10.1038/s41413-022-00193-1 |
Ejemplares similares
-
Peptide modified geniposidic acid targets bone and effectively promotes osteogenesis
por: Liu, Meijing, et al.
Publicado: (2022) -
Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models
por: Rivas-Santiago, Bruno, et al.
Publicado: (2013) -
IDR knowledge base for primary immunodeficiencies
por: Samarghitean, Crina, et al.
Publicado: (2007) -
IDR muon capture front end and variations
por: Neuffer, David, et al.
Publicado: (2012) -
IDR2D identifies reproducible genomic interactions
por: Krismer, Konstantin, et al.
Publicado: (2020)