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NLRP3 priming due to skin damage precedes LTP allergic sensitization in a mouse model

Allergic sensitization is initiated by protein and epithelia interaction, although the molecular mechanisms leading this encounter toward an allergic phenotype remain unknown. Here, we apply the two-hit hypothesis of inflammatory diseases to the study of food allergy sensitization. First, we studied...

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Detalles Bibliográficos
Autores principales: Pazos-Castro, Diego, Gonzalez-Klein, Zulema, Montalvo, Alma Yuste, Hernandez-Ramirez, Guadalupe, Romero-Sahagun, Alejandro, Esteban, Vanesa, Garrido-Arandia, Maria, Tome-Amat, Jaime, Diaz-Perales, Araceli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885703/
https://www.ncbi.nlm.nih.gov/pubmed/35228630
http://dx.doi.org/10.1038/s41598-022-07421-y