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Dynamics of Neuromuscular Transmission Reproduced by Calcium-Dependent and Reversible Serial Transitions in the Vesicle Fusion Complex

Neuromuscular transmission, from spontaneous release to facilitation and depression, was accurately reproduced by a mechanistic kinetic model of sequential maturation transitions in the molecular fusion complex. The model incorporates three predictions. First, calcium-dependent forward transitions t...

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Detalles Bibliográficos
Autores principales: Martínez-Valencia, Alejandro, Ramírez-Santiago, Guillermo, De-Miguel, Francisco F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8885725/
https://www.ncbi.nlm.nih.gov/pubmed/35242023
http://dx.doi.org/10.3389/fnsyn.2021.785361